March 4, 2022

Bulletin Health Topic - Fisetin

Fisetin


Fisetin is a naturally occurring flavonoid that positively impacts our health and well being.


Flavonoids are the healthy bit of fruit and vegetables that give them their bright colours. Human cells can only grow and divide so many times. They turn senescent (zombie cells) and accumulate everywhere in the body.


Senescent cells secrete damaging substances that affect healthy surrounding cells and can disrupt stem cells. They also promote low levels of chronic inflammation. 


Accumulation of the senescent cells drives ageing and all age related diseases. It’s important to clear away these senescent cells.


Senolytics are molecules the body uses to clear away the senescent cells. Fisetin is a very potent senolytic.

It clears away senescent cells without damaging healthy cells. This has many health and longevity benefits.


Fisetin is a powerful antioxidant that protects cells from free radical damage. It also preserves the bodies supply of glutathione. An important antioxidant that declines as we age. Low levels of glutathione are linked to all aged related diseases.


Fisetin has been shown to mimic calorie restriction. When we calorie restrict our body will go into survival mode and release sirtuins, the repairers of our body.


Fisetin will activate the sirtuin function in our cells. Fisetin has been shown to have anti-cancer properties. It has the ability to induce apoptosis (cell death) in cancer and help in the removal of tumour cells.


The Mayo Clinic has now engaged in a comprehensive study of the anti aging benefits of Fisetin. Fisetin other benefits is that it's contained in delicious fruit and veg. This can be a welcome relief for people who find it hard to eat sardines for breakfast.


FISETIN FOODS:

  • Strawberries
  • Apples
  • Mangoes
  • Persimmons
  • Kiwi fruit
  • Tomatoes
  • Onions
  • Cucumbers and,
  • Nuts


Another way that has a greater concentration of absorbable fisetin is to supplement, have a chat with Pete the next time you are in to find out where, when and how you can supplement! In the meantime, check out our amazing Fisetin rich salad recipe below! ( click on the image for the full recipe).

By Zina Stone October 24, 2025
In this bulletin...
By Zina Stone October 24, 2025
Ingredients 700 g grass-fed beef strips (sirloin, flank, or rump steak) 4 large portobello mushrooms (approx. 400 g total) 8 medium carrots, peeled and halved lengthwise (about 600 g) 2 bunches broccolini (approx. 400 g) 6½ tbsp olive oil total (≈ 97 mL) (2 tbsp for beef + 2 tbsp for mushrooms + 1½ tbsp for carrots + 1 tbsp for broccolini) 1 tbsp butter (14 g) 2 cloves garlic, minced (6 g) 1 tbsp fresh rosemary or thyme, chopped (optional) 2 tsp salt total (≈ 12 g) (½ tsp for beef + ½ tsp for mushrooms + ½ tsp for carrots + ½ tsp for broccolini) 1¼ tsp black pepper total (≈ 5 g) 1 tbsp balsamic vinegar (optional, 15 mL) 1 tsp honey or maple syrup (optional, 7 g) Instructions 1. Roast the carrots and mushrooms Preheat the oven to 200°C (400°F) . Line a baking tray with parchment paper. Toss carrots with olive oil, salt, pepper, and honey/maple syrup if using. Spread on half of the tray. Place the portobello mushrooms on the other half, drizzle with olive oil and balsamic (if using), and season with salt and pepper. Roast for 25–30 minutes , turning once halfway through. Mushrooms should be tender and juicy; carrots caramelized and golden. 2. Grill the beef While vegetables roast, heat a grill pan or barbecue over high heat . Toss beef strips with olive oil, garlic, herbs, salt, and pepper. Grill for 2–3 minutes per side , or until cooked to your liking (medium-rare to medium recommended). Rest for a few minutes before serving to keep tender and juicy. 3. Steam and fry the broccolini Bring a small pot of water to a boil, and lightly steam broccolini for 2–3 minutes until bright green. Drain well. Heat butter and olive oil in a frying pan over medium-high heat . Add the broccolini and sauté for 2–3 minutes , seasoning with salt and pepper until slightly crisp on the edges. 4. Serve Plate each portion with a serving of grilled beef strips, a whole roasted mushroom, a few roasted carrots, and a generous side of buttery broccolini. Drizzle any beef or mushroom juices over the top for extra flavor. Optional Garnish Sprinkle with fresh parsley or thyme before serving. Add a squeeze of lemon over the broccolini for brightness. Nutrition and Cooking Times Serves: 4 | Prep time: 15 minutes | Cook time: 30–35 minutes Nutrient Value per serve: Calories: 480kcal | Protein: 39g | Fat: 28g | Carbohydrates: 15g
By Zina Stone October 24, 2025
In this bulletin...